Unwanted Kit – Is it safe? Uses, Side effects, Dosage

 What is Unwanted kit?

Unwanted kit (200 mg or 200 mcg) tablets (otherwise known as RU-486) is a synthetically produced steroid drug and is used in combination with misoprostol. It is produced by Mankind Pharma Ltd.

• It is primarily used in the terminating process of pregnancy, the abortion in women who have been pregnant for about Seven weeks or Fifty days.
• The function of this kit is to interfere in the pregnancy hormone.
• Generally, this drug can be brought even without the prescription of the physician.

Unwanted Kit – Is it safe? Uses, Side effects, Dosage

What is the Generic name(s)?
What is its composition?
How does Unwanted Kit work?
What are its uses?
How effective is Unwanted Kit?
Is it addictive?
What is the dosage?
What if I miss a dose?
What to do in case of overdosage?
Can I drive after taking it?
Can it be taken on an empty stomach?
Can it be taken with food?
Can I take it with alcohol?
What are the side effects of Unwanted Kit?
Does this medicine has any drug interactions?
Precautions
Is it safe to use if I am pregnant?
Is it safe to use if I am breastfeeding?
Can this medicine be given to children and infants?
Is Unwanted kit available as over the counter (OTC) product?
Frequently asked questions
Reference

What is the Generic Name(s)?

The generic name(s) of unwanted kit is based on its presence of active ingredients. The names are Mifepristone and Misoprostol tablets.

What is its composition?

This unwanted kit is mainly composed of two active ingredients. They are

• Mifepristone – 200 mg
• Misoprostol ( which is also known as Cytotec) – 200 mcg

How does unwanted kit work?

This medicine’s primary function is to terminate the pregnancy by aborting the foetus. It works by competitively binding to the specific receptors and sensitizing the inner linings present in the uterus which in turn induce the bleeding and contractions in the abdominal area. It then results in the blocking the effect of progesterone, a pregnancy hormone and leads to the termination of pregnancy. This also prevents the formation of an ulcer.

This action of this drug also involved in the reduction of cortisone hormone’s effects by the excessive presence of this hormone. It occurs by binding with the particular receptors and blocks the action of the hormone.

What are its uses?

The unwanted kit tablets are used in the treatment and prevention of the following conditions:

• Medical termination of pregnancy
• Termination of early pregnancy (Legal abortion)
• Cushing’s syndrome
• Loss of blood
• Breast cancer
• Endometriosis
• Benign Gastric ulcer
• Duodenal Ulcer
• Gastrointestinal injury associated with NSAIDs (Non-Steroidal Anti Inflammatory Drugs)
• Meningioma
• Labour induction in fetus mortus
• Malignancies depend on Progesterone
• Extrauterine pregnancy
• Induction of menses
• Contraception with intermittent administration
• Immediate postcoital emergency contraception
• Cervical ripening before surgical termination of pregnancy

How effective is this medicine?

This effectiveness of this drug is quite good. The unwanted kit medicine is easily absorbed through the bloodstream if it is taken as oral administration. It starts its onset of action within 1 to 2 hours. The effectiveness of this drug lasts long up to a period of seven to ten days.

Is it addictive?

No, this drug is not addictive. It is not reported to have any addictive or habit-forming tendencies.

What is the Dosage?

The dosage of this medication depends upon the various conditions. It can vary on age and weight of the person, pre-medical history, the gender of the person, overall health and current condition. The doctor considers all these factors before suggesting the correct dosage.

The common dose used for abortion is about 200 mg per day. After two or three days, the dosage may be decreased up to 800 mcg per day. After a week, the drug can be stopped with the instruction of your physician.

What if I miss a dose?

• In case of medical termination of pregnancy, it should be taken as single dose therapy. Hence, missing a dose of this drug is not possible in this case.
• On another hand, if this drug is used in the control of elevated blood sugar level, try to take the drug immediately once you remember it. But if it is already the time for the next dosage, just go on and continue with your regular dosage. It is because it may result in the overdosage of this medicine. Always follow the doctor’s advice in such cases.

What to do in case of overdosage?

If you consumed this drug in overdosage, consult your doctor as soon as possible to avoid undesirable effects. The overdosage of this drug may result in serious side effects such as Vaginal bleeding and inflammation in the vaginal area.

Can I drive after taking it?

After consuming these tablets, if you feel dizziness or drowsiness, avoid driving any vehicle or operating any heavy types of machinery. It can result in lowering your concentration on the situation. Contact your doctor if you experience any abnormalities.

Can it be taken on an empty stomach?

There are no specific instructions that it should be taken on an empty stomach. But it is recommended to take this tablet after food. So take it as per the instructions given by your physician.

Can it be taken with food?

Although there are no particular instructions that it should be taken with food, it is generally advised to take it after food. Hence, consult your physician and take the drug as per his/her advice.

Can I take it with alcohol?

No, this medicine must not be taken with alcohol. This drug, when it interacts with the alcohol, will increase the effect of dizziness or drowsiness by increasing blood pressure level.

What are the side effects?

Though the drug can cause intended effects, it can also cause a person to experience various unwanted side effects. Such reported side effects are listed below:

• Heavy vaginal bleeding
• Infectious effects
• Unusual Tiredness and Weakness
• Cramps and pain in Abdominal region
• Nausea and vomiting
• Cramping in the uterine area
• Irregular heartbeat (too fast or too slow)
• Headache
• Severe dizziness and drowsiness
• Diarrhoea
• A decrease in the level of Appetite
• Insomnia (Sleeplessness or Troubled sleeping)
• Difficulty in urination
• Pain in the vaginal region while urination
• The difficult or painful breathing process
• Loss of Strength
• Fatigue
• Cough and fever
• Sweating and Lightheadedness
• Anxiety
• Paleness
• Tremors
• Acidity and Indigestion
• Body sores
• Inflammation of nasal sinus
• Back pain
• Cramps in the gastrointestinal region
• Pain during sexual intercourse
• Constipation

Does this medicine has any drug interactions?

Some drugs which interact with an unwanted tablet will not allow it to work properly or else it may result in serious side effects. The effect will change according to the specific drug which would cause interactions. Those drugs are listed below:

• Danaparoid
• Cervidi
• Bepridil
• Aspirin
• Ceritinib
• Amprenavir
• Corticotropin
• Ergometrine
• Gemeprost
• Dinoprostone topical
• Medications which are used to treat hepatitis B and HIV
• Antifungal or antibiotic drugs
• Seizure medication and Tuberculosis medication
• Medication used for  heart disease or blood pressure

Precautions

There are some precautions and warnings which you have to follow before taking this drug. Consult your doctor before using this drug if you have the following conditions to experience better results:

• Inform your doctor if you are allergic to the active ingredients present in the medicine.
• Let your physician know if you are allergic to prostaglandins.
• Consult your doctor if you are taking steroid drugs for a long period of time.
• Avoid this drug if the baby is formed outside the region of the uterus (ectopic pregnancy or molar pregnancy).
• Consult your doctor if you are older than 35 years as this medicine won’t show its maximum effect on your condition.
• Let your doctor know if you are a chain smoker.
• Always consult your doctor if you are taking any drugs such as Anticoagulants, Dietary supplements, Vitamin supplements or Herbal supplements.
• Consult your doctor if you have a pre-medical history such as Asthma, liver, kidney or lung diseases.

Is it safe to take if I am pregnant?

Actually, this tablet is used in the process of terminating the pregnancy. It should be used within 63 to 7o days of being pregnant. So it should not be taken after the mentioned period of time as it may affect both mental and physical health of the foetus. But, regarding the pregnancy warnings, if this drug failed to terminate the pregnancy, it may lead to the life-threatening complicated situations. It is usually recommended to control increased blood sugar level. However, it is not used in pregnant women who are reported to have elevated corticosterone levels. Hence, consult your doctor regarding the use of this medicine if you are pregnant and strictly follow the doctor’s advice accordingly.

Is it safe to take if I am breastfeeding?

No, this medicine is not safe to take if you are breastfeeding. This is due to the presence of Mifepristone. It is observed that this drug may pass into the breast milk which can cause dangerous side effects in infants. So, if you are planning to consume this tablet, stop feeding the infant. Also, it is always safe and better to consult your physician immediately regarding the issue.

Can this medicine be given to Children and Infants?

No, this medicine cannot be given to Children and Infants. It is actually recommended for women only.

Is this medicine available as Over the Counter (OTC) product?

Yes, this medicine is available as Over The Counter (OTC) product.

Frequently asked questions

How to store this drug?

This tablet should not be kept in direct heat, moisture or heat. It is recommended to store the drug in a temperature ranging between 15 degree Celsius to 25-degree Celsius, which is the room temperature. Unless it is mentioned on the package, this drug should not be placed in the refrigerator at freezing temperatures. Store this drug far away from children and pet to avoid unwanted effects.

This tablet should not be discarded by flushing in toilet or sink. This kind of improper disposal of these tablets may affect human hygiene and health by contaminating the environment.

What happens if I take an expired drug?

This drug would lose its effectiveness and potency when it gets expired. If you take this expired drug, it won’t have the capacity to treat the condition and it may fail in the termination of pregnancy. It may cause adverse effects which can result in worsening heart conditions and seizures. Always consult with your doctor regarding the handling of the expired drug and always be careful about noting the expiry date as mentioned on the drug packaging.

What to do if there is an allergic reaction?

The allergic reactions caused by this drug are rare and unusual. Therefore, it is strongly recommended to consult your physician as soon as possible if you face any of the following allergic conditions:

• Troubled (or difficult or painful) Breathing
• Inflammation in the vaginal area

What is the price of this drug?

This unwanted kit costs about Rupees 385 (for a single kit).

When to avoid this drug?

Hypersensitivity is the contraindication of this drug. Although it is safe to avoid this drug if you have the following medical conditions,

• Hypersensitivity
• Suspected ectopic pregnancy
• Pregnancy and breastfeeding
• Cardiovascular disease
• Cerebrovascuar disease
• Chronic and acute adrenal failure
• Renal impairment
• Haemorrhagic disorder ( bleeding or blood clotting disorder)
• Inherited porphyrias ( a genetic enzyme disorder that affects the skin or nervous system)
• History of uterine rupture or uterine scar

How to take this drug?

This drug is usually administrated in the oral route. Usually, one can keep the tablet inside the cheek pouch or under the tongue. The remnants can be swallowed. Take this drug once in a day for a week. After 7 days, consult your doctor about the bleeding and its quantity and frequency for effective result. Always follow the doctor’s advice and do carefully read all the information and instructions printed on the drug packaging.

Are there any particular food items to be avoided while taking this drug?

No, there are no particular food items to be avoided while taking this drug. Do consult with your doctor before using this medicine.

Can this drug be stopped abruptly?

No, this drug should not be stopped abruptly as it may result in rebound effects. Stopping this drug abruptly without any advice from your doctor may lead to the failure in the termination of the pregnancy.

 

Can this kit be used for both pregnancy termination and early pregnancy termination?

Yes, this kit can be used for both pregnancy termination and early pregnancy termination. It is due to the presence of its effective active ingredients and so this drug is used in the pregnancy termination by aborting the foetus in the uterus by binding to the specific receptors.

Is there any other condition for which this drug is prescribed?

This drug is prescribed for Cushing’s syndrome, primarily to control the increased blood sugar level in patients who have diabetes or glucose syndrome.

Reference

Wikipedia page on Birth control

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